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Crohn's Disease Exclusion Diet Plus Partial Enteral Nutrition Induces Sustained Remission in a Randomized Controlled Trial
Abstract
Details
Title
Crohn's Disease Exclusion Diet Plus Partial Enteral Nutrition Induces Sustained Remission in a Randomized Controlled Trial
Type of Article
Primary Research
Diets studied
CDED
PEN
Date
August 1, 2019
Author(s)
Levine A et al
Publication
Gastroenterology
Citation
Levine, A., Wine, E., Assa, A., Sigall Boneh, R., Shaoul, R., Kori, M., Cohen, S., Peleg, S., Shamaly, H., On, A., Millman, P., Abramas, L., Ziv-Baran, T., Grant, S., Abitbol, G., Dunn, K. A., Bielawski, J. P., & Van Limbergen, J. (2019). Crohn’s Disease Exclusion Diet Plus Partial Enteral Nutrition Induces Sustained Remission in a Randomized Controlled Trial. Gastroenterology, 157(2), 440-450.e8. https://doi.org/10.1053/j.gastro.2019.04.021
ISSN Number
00165085
Volume
157
Pages
440-450.e8
CDED plus PEN was better tolerated than EEN in children with mild to moderate CD. Both diets were effective in inducing remission by week 6. The combination CDED plus PEN induced sustained remission in a significantly higher proportion of patients than EEN, and produced changes in the fecal microbiome associated with remission. These data support use of CDED plus PEN to induce remission in children with CD.
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