Food as Treatment of Inflammatory Bowel Diseases

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Food as Treatment of Inflammatory Bowel Diseases

Abstract

Inflammatory bowel diseases (IBD), namely, Crohn's disease (CD) and ulcerative colitis (UC), are lifelong and incurable chronic inflammatory diseases affecting 6.8 million people worldwide. By 2030, the prevalence of IBD is estimated to reach 1% of the population in Western countries, and thus there is an urgent need to develop effective therapies to reduce the burden of this disease. Microbiome dysbiosis is at the heart of the IBD pathophysiology, and current research and development efforts for IBD treatments have been focused on gut microbiome regulation. Diet can shape the intestinal microbiome. Diet is also preferred over medication, is safe, and has been proven to be an effective strategy for the management of IBD. Therefore, although often overlooked, dietary interventions targeting the microbiome represent ideal treatments for IBD. Here, I summarize the latest research on diet as a treatment for IBD from infancy to adulthood, compile evidence of the mechanisms of action behind diet as treatment, and, lastly, provide insights into future research focusing on culturally tailored diets for ethnic minority groups with increased incidence of IBD yet underrepresented in nutrition research.

Details
Title
Food as Treatment of Inflammatory Bowel Diseases
Type of Article
Review Article - Concept Article
Diets studied
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Date
May 19, 2022
Author(s)
Maldonado-Contreras, A
Publication
Infection and Immunity
Citation

Maldonado-Contreras, A. (2022). Food as Treatment of Inflammatory Bowel Diseases. Infection and Immunity, 90(5), e00583-21. https://doi.org/10.1128/iai.00583-21

ISSN Number
0019-9567, 1098-5522
Volume
90
Pages
e00583-21

The latest research on diet as treatment in inflammatory bowel disease is summarized with evidence for mechanisms behind diet as treatment.

Somebody in the kitch - view from the back while preparing healthy foods. Cutting board with various healthy foodsPink Milkshake and fruits on a white table and pink backgroundWoman stirring in a pot with vegetables.on the stove

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