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Randomised Clinical Trial: Exclusive Enteral Nutrition Versus Standard of Care for Acute Severe Ulcerative Colitis
Abstract
Details
Title
Randomised Clinical Trial: Exclusive Enteral Nutrition Versus Standard of Care for Acute Severe Ulcerative Colitis
Type of Article
Primary Research
Diets studied
EEN
Date
January 13, 2021
Author(s)
Sahu P et al
Publication
Alimentary Pharmacology & Therapeutics
Citation
Sahu, P., Kedia, S., Vuyyuru, S. K., Bajaj, A., Markandey, M., Singh, N., Singh, M., Kante, B., Kumar, P., Ranjan, M., Sahni, P., Panwar, R., Sharma, R., Das, P., Makharia, G., Travis, S. P. L., & Ahuja, V. (2021). Randomised clinical trial: exclusive enteral nutrition versus standard of care for acute severe ulcerative colitis. Alimentary Pharmacology & Therapeutics. https://doi.org/10.1111/apt.16249
ISSN Number
02692813
Volume
Pages
Patients on EEN had a shorter hospital stay [median (range) 10 (8-17) vs 13 (8-24) days; P = 0.04], higher day 7 albumin level (34 ± 4 vs 29 ± 3 g/L, P < 0.01), greater reduction in serum C-reactive protein and faecal calprotectin levels (both P = 0.04) and a lower composite outcome of colectomy/hospitalisation at 6 months (16% vs 39%; P = 0.045) compared to SOC.
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