Response to Strict and Liberalized Specific Carbohydrate Diet in Pediatric Crohn's Disease

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Response to Strict and Liberalized Specific Carbohydrate Diet in Pediatric Crohn's Disease

Abstract

AIM: To investigate the specific carbohydrate diet (SCD) as nutritional therapy for maintenance of remission in pediatric Crohn's disease (CD)., METHODS: Retrospective chart review was conducted in 11 pediatric patients with CD who initiated the SCD as therapy at time of diagnosis or flare. Two groups defined as SCD simple (diet alone, antibiotics or 5-ASA) or SCD with immunomodulators (corticosteroids and/or stable thiopurine dosing) were followed for one year and compared on disease characteristics, laboratory values and anthropometrics., RESULTS: The mean age at start of the SCD was 11.8 ± 3.0 years (range 6.6-17.6 years) with five patients starting the SCD within 5 wk of diagnosis. Three patients maintained a strict SCD diet for the study period and the mean time for liberalization was 7.7 ± 4.0 mo (range 1-12) for the remaining patients. In both groups, hematocrit, albumin and ESR values improved while on strict SCD and appeared stable after liberalization (P-value 0.006, 0.002, 0.002 respectively). The majority of children gained in weight and height percentile while on strict SCD, with small loss in weight percentile documented with liberalization., CONCLUSION: Disease control may be attainable with the SCD in pediatric CD. Further studies are needed to assess adherence, impact on mucosal healing and growth.

Details
Title
Response to Strict and Liberalized Specific Carbohydrate Diet in Pediatric Crohn's Disease
Type of Article
Primary Research
Diets studied
SCD
Date
February 1, 2016
Author(s)
Burgis JC et al
Publication
World Journal of Gastroenterology
Citation

Burgis, J. C., Nguyen, K., Park, K., & Cox, K. (2016). Response to strict and liberalized specific carbohydrate diet in pediatric Crohn’s disease. World Journal of Gastroenterology, 22(6), 2111–2117. https://doi.org/10.3748/wjg.v22.i6.2111

ISSN Number
1007-9327
Volume
22
Pages
2111-2117

Disease control may be attainable with the SCD in pediatric CD. Further studies are needed to assess adherence, impact on mucosal healing and growth.

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