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The Autoimmune Protocol Diet Modifies Intestinal RNA Expression in Inflammatory Bowel Disease

The Autoimmune Protocol Diet Modifies Intestinal RNA Expression in Inflammatory Bowel Disease

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Abstract

Lay Summary Researchers from the Scripps Clinic in La Jolla, CA recently looked at gene expression to better understand the role that diet plays in inflammatory bowel disease. Their findings suggest that diet may help modify inflammatory pathways in people with ulcerative colitis.

Details
Title
The Autoimmune Protocol Diet Modifies Intestinal RNA Expression in Inflammatory Bowel Disease
Type of Article
Primary Research
Diets studied
AIP
Date
October 1, 2019
Author(s)
Chandrasekaran A et al
Publication
Crohn's & Colitis 360
Citation

Chandrasekaran, A., Molparia, B., Akhtar, E., Wang, X., Lewis, J. D., Chang, J. T., Oliveira, G., Torkamani, A., & Konijeti, G. G. (2019). The Autoimmune Protocol Diet Modifies Intestinal RNA Expression in Inflammatory Bowel Disease. Crohn’s & Colitis 360, 1(3), otz016. https://doi.org/10.1093/crocol/otz016

ISSN Number
2631-827X
Volume
1
Pages
otz016

Results from this RNA substudy would suggest dietary elimination, along with emphasis on a nutrient-dense diet, has the potential to positively modify inflammation and reduce symptoms in UC. Our substudy, though very small, included a well-defined subgroup of participants with UC on mesalamine only, avoiding effects that might be attributable to systemic or targeted immunosuppression.

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Somebody in the kitch - view from the back while preparing healthy foods. Cutting board with various healthy foodsPink Milkshake and fruits on a white table and pink backgroundWoman stirring in a pot with vegetables.on the stove

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